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Unbiased probing of the entire hepatitis C virus life cycle identifies clinical compounds that target multiple aspects of the infection

Over 170 million people are chronically infected by the hepatitis C virus (HCV) and at risk for dying from liver cirrhosis and hepatocellular carcinoma. Current therapy is expensive, associated with significant side effects, and often ineffective. Discovery of antiviral compounds against HCV traditi...

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Autors principals: Gastaminza, Pablo, Whitten-Bauer, Christina, Chisari, Francis V.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806752/
https://ncbi.nlm.nih.gov/pubmed/19995961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912966107
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