Antiviral Stilbene 1,2-Diamines Prevent Initiation of Hepatitis C Virus RNA Replication at the Outset of Infection

The recent development of a cell culture model of hepatitis C virus (HCV) infection based on the JFH-1 molecular clone has enabled discovery of new antiviral agents. Using a cell-based colorimetric screening assay to interrogate a 1,200-compound chemical library for anti-HCV activity, we identified...

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Detalhes bibliográficos
Main Authors: Gastaminza, Pablo, Pitram, Suresh M., Dreux, Marlene, Krasnova, Larissa B., Whitten-Bauer, Christina, Dong, Jiajia, Chung, Josan, Fokin, Valery V., Sharpless, K. Barry, Chisari, Francis V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094966/
https://ncbi.nlm.nih.gov/pubmed/21430055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02116-10
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