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CD4(+) T cell regulation of CD25 expression controls development of short-lived effector CD8(+) T cells in primary and secondary responses

Both CD4(+) T cell help and IL-2 have been postulated to “program” activated CD8(+) T cells for memory cell development. However, the linkage between these two signals has not been well elucidated. Here we have studied effector and memory CD8(+) T cell differentiation following infection with three...

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Détails bibliographiques
Auteurs principaux: Obar, Joshua J., Molloy, Michael J., Jellison, Evan R., Stoklasek, Thomas A., Zhang, Weijun, Usherwood, Edward J., Lefrançois, Leo
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806751/
https://ncbi.nlm.nih.gov/pubmed/19966302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909945107
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