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CRYSTAL STRUCTURE OF PROLYL 4-HYDROXYLASE FROM BACILLUS ANTHRACIS

Prolyl 4-hydroxylases (P4H) catalyze the posttranslational hydroxylation of proline residues and play a role in collagen production, hypoxia response, and cell wall development. P4Hs belong to the Fe(II)/αKG oxygenases and require Fe(II), α-ketoglutarate (αKG), and O(2) for activity. We report the 1...

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Detalhes bibliográficos
Main Authors: Culpepper, Megen A., Scott, Emily E., Limburg, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806640/
https://ncbi.nlm.nih.gov/pubmed/19947658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi901771z
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