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Bacillus anthracis Prolyl 4-Hydroxylase Modifies Collagen-like Substrates in Asymmetric Patterns

Proline hydroxylation is the most prevalent post-translational modification in collagen. The resulting product trans-4-hydroxyproline (Hyp) is of critical importance for the stability and thus function of collagen, with defects leading to several diseases. Prolyl 4-hydroxylases (P4Hs) are mononuclea...

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Vydáno v:J Biol Chem
Hlavní autoři: Schnicker, Nicholas J., Dey, Mishtu
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4933245/
https://ncbi.nlm.nih.gov/pubmed/27129244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.725432
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