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The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses
BACKGROUND: Histone deacetylase inhibitors (HDACIs) induce hyperacetylation of core histones modulating chromatin structure and affecting gene expression. These compounds are also able to induce growth arrest, cell differentiation, and apoptotic cell death of tumor cells in vitro as well as in vivo....
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| Published in: | BMC Cancer |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BMC
2003
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280656/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14606959/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2407-3-30 |
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