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The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses
BACKGROUND: Histone deacetylase inhibitors (HDACIs) induce hyperacetylation of core histones modulating chromatin structure and affecting gene expression. These compounds are also able to induce growth arrest, cell differentiation, and apoptotic cell death of tumor cells in vitro as well as in vivo....
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
BioMed Central
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC280656/ https://ncbi.nlm.nih.gov/pubmed/14606959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-3-30 |
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