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The histone deacetylase inhibitor Trichostatin A modulates CD4+ T cell responses

BACKGROUND: Histone deacetylase inhibitors (HDACIs) induce hyperacetylation of core histones modulating chromatin structure and affecting gene expression. These compounds are also able to induce growth arrest, cell differentiation, and apoptotic cell death of tumor cells in vitro as well as in vivo....

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Publicat a:BMC Cancer
Autors principals: Moreira, José Manuel Afonso, Scheipers, Peter, Sørensen, Poul
Format: Artigo
Idioma:Inglês
Publicat: BMC 2003
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280656/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14606959/
https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2407-3-30
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