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Treatment of biliary tract cancer with NVP-AEW541: Mechanisms of action and resistance

AIM: To investigate in vitro treatment with NVP-AEW541, a small molecule inhibitor of insulin-like growth factor-1 receptor (IGF-1R), in biliary tract cancer (BTC), since this disease is associated with a poor prognosis due to wide resistance to chemotherapeutic agents and radiotherapy. METHODS: Cel...

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Bibliografiske detaljer
Main Authors: Wolf, Samuel, Lorenz, Jana, Mössner, Joachim, Wiedmann, Marcus
Format: Artigo
Sprog:Inglês
Udgivet: Baishideng 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806553/
https://ncbi.nlm.nih.gov/pubmed/20066734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v16.i2.156
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