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Inhibition of histone deacetylase for the treatment of biliary tract cancer: A new effective pharmacological approach

AIM: To investigate in vitro and in vivo therapeutic effects of histone deacetylase inhibitors NVP-LAQ824 and NVP-LBH589 on biliary tract cancer. METHODS: Cell growth inhibition by NVP-LAQ824 and NVP-LBH589 was studied in vitro in 7 human biliary tract cancer cell lines by MTT assay. In addition, th...

詳細記述

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書誌詳細
出版年:World J Gastroenterol
主要な著者: Bluethner, Thilo, Niederhagen, Manuel, Caca, Karel, Serr, Frederik, Witzigmann, Helmut, Moebius, Christian, Mossner, Joachim, Wiedmann, Marcus
フォーマット: Artigo
言語:Inglês
出版事項: Baishideng Publishing Group Co., Limited 2007
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611198/
https://ncbi.nlm.nih.gov/pubmed/17729398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i35.4761
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