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Inhibition of histone deacetylase for the treatment of biliary tract cancer: A new effective pharmacological approach

AIM: To investigate in vitro and in vivo therapeutic effects of histone deacetylase inhibitors NVP-LAQ824 and NVP-LBH589 on biliary tract cancer. METHODS: Cell growth inhibition by NVP-LAQ824 and NVP-LBH589 was studied in vitro in 7 human biliary tract cancer cell lines by MTT assay. In addition, th...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Bluethner, Thilo, Niederhagen, Manuel, Caca, Karel, Serr, Frederik, Witzigmann, Helmut, Moebius, Christian, Mossner, Joachim, Wiedmann, Marcus
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Co., Limited 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4611198/
https://ncbi.nlm.nih.gov/pubmed/17729398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i35.4761
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