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Inhibition of histone deacetylase for the treatment of biliary tract cancer: A new effective pharmacological approach
AIM: To investigate in vitro and in vivo therapeutic effects of histone deacetylase inhibitors NVP-LAQ824 and NVP-LBH589 on biliary tract cancer. METHODS: Cell growth inhibition by NVP-LAQ824 and NVP-LBH589 was studied in vitro in 7 human biliary tract cancer cell lines by MTT assay. In addition, th...
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Publicado no: | World J Gastroenterol |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Baishideng Publishing Group Co., Limited
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4611198/ https://ncbi.nlm.nih.gov/pubmed/17729398 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v13.i35.4761 |
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