Direct recognition of the mycobacterial glycolipid, trehalose dimycolate, by C-type lectin Mincle

Tuberculosis remains a fatal disease caused by Mycobacterium tuberculosis, which contains various unique components that affect the host immune system. Trehalose-6,6′-dimycolate (TDM; also called cord factor) is a mycobacterial cell wall glycolipid that is the most studied immunostimulatory componen...

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Detalhes bibliográficos
Main Authors: Ishikawa, Eri, Ishikawa, Tetsuaki, Morita, Yasu S., Toyonaga, Kenji, Yamada, Hisakata, Takeuchi, Osamu, Kinoshita, Taroh, Akira, Shizuo, Yoshikai, Yasunobu, Yamasaki, Sho
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
Assuntos:
Brief Definitive Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806462/
https://ncbi.nlm.nih.gov/pubmed/20008526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20091750
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