Učitavanje...
Valosin-containing protein (VCP) is required for autophagy and is disrupted in VCP disease
Mutations in valosin-containing protein (VCP) cause inclusion body myopathy (IBM), Paget's disease of the bone, and frontotemporal dementia (IBMPFD). Patient muscle has degenerating fibers, rimmed vacuoles (RVs), and sarcoplasmic inclusions containing ubiquitin and TDP-43 (TARDNA-binding protei...
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| Glavni autori: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Rockefeller University Press
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806317/ https://ncbi.nlm.nih.gov/pubmed/20008565 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200908115 |
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