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TFB2 is a transient component of the catalytic site of the human mitochondrial RNA polymerase
Transcription in human mitochondria is carried out by a single-subunit, T7-like RNA polymerase assisted by several auxiliary factors. We demonstrate that an essential initiation factor, TFB2, forms a network of interactions with DNA near the transcription start site and facilitates promoter melting...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2806307/ https://ncbi.nlm.nih.gov/pubmed/19945377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.10.031 |
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