Identification of a novel germ-line mutation in the TP53 gene in a Mexican family with Li-Fraumeni syndrome

BACKGROUND: Germ-line mutations of the TP53 gene are known to cause Li-Fraumeni syndrome, an autosomal, dominantly inherited, high-penetrance cancer-predisposition syndrome characterized by the occurrence of a variety of cancers, mainly soft tissue sarcomas, adrenocortical carcinoma, leukemia, breas...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Taja-Chayeb, Lucia, Vidal-Millán, Silvia, Gutiérrez-Hernández, Olga, Trejo-Becerril, Catalina, Pérez-Cárdenas, Enrique, Chávez-Blanco, Alma, de la Cruz-Hernández, Erick, Dueñas-González, Alfonso
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2009
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806269/
https://ncbi.nlm.nih.gov/pubmed/20017945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1477-7819-7-97
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg