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Unpacking a gel-forming mucin: a view of MUC5B organization after granular release

Gel-forming mucins are the largest complex glycoprotein macromolecules in the body. They form the matrix of gels protecting all the surface epithelia and are secreted as disulfide-bonded polymeric structures. The mechanisms by which they are formed and organized within cells and thereafter released...

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Autors principals: Kesimer, Mehmet, Makhov, Alexander M., Griffith, Jack D., Verdugo, Pedro, Sheehan, John K.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806194/
https://ncbi.nlm.nih.gov/pubmed/19783639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00194.2009
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