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Nonanticoagulant heparin reduces myocyte Na(+) and Ca(2+) loading during simulated ischemia and decreases reperfusion injury

Heparin desulfated at the 2-O and 3-O positions (ODSH) decreases canine myocardial reperfusion injury. We hypothesized that this occurs from effects on ion channels rather than solely from anti-inflammatory activities, as previously proposed. We studied closed-chest pigs with balloon left anterior d...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Barry, William H., Zhang, Xiu Q., Halkos, Michael E., Vinten-Johansen, Jakob, Saegusa, Noriko, Spitzer, Kenneth W., Matsuoka, Nobuhiro, Sheets, Michael, Rao, Narayanam V., Kennedy, Thomas P.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Physiological Society 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806141/
https://ncbi.nlm.nih.gov/pubmed/19855066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00316.2009
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