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Transient receptor potential ankyrin-1 has a major role in mediating visceral pain in mice

The excitatory ion channel transient receptor potential ankyrin-1 (TRPA1) is prominently expressed by primary afferent neurons and is a mediator of inflammatory pain. Inflammatory agents can directly activate [e.g., hydroxynonenal (HNE), prostaglandin metabolites] or indirectly sensitize [e.g., agon...

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Detalhes bibliográficos
Main Authors: Cattaruzza, Fiore, Spreadbury, Ian, Miranda-Morales, Marcela, Grady, Eileen F., Vanner, Stephen, Bunnett, Nigel W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806099/
https://ncbi.nlm.nih.gov/pubmed/19875705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00221.2009
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