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An Overview of Chemical Processes That Damage Cellular DNA: Spontaneous Hydrolysis, Alkylation, and Reactions with Radicals

The sequence of heterocyclic bases on the interior of the DNA double helix constitutes the genetic code that drives the operation of all living organisms. With this said, it is not surprising that chemical modification of cellular DNA can have profound biological consequences. Therefore, the organic...

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Detalhes bibliográficos
Autor principal: Gates, Kent S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806061/
https://ncbi.nlm.nih.gov/pubmed/19757819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx900242k
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