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Chemical biology of mutagenesis and DNA repair: cellular responses to DNA alkylation
The reaction of DNA-damaging agents with the genome results in a plethora of lesions, commonly referred to as adducts. Adducts may cause DNA to mutate, they may represent the chemical precursors of lethal events and they can disrupt expression of genes. Determination of which adduct is responsible f...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2802671/ https://ncbi.nlm.nih.gov/pubmed/19875697 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgp262 |
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