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Combination flucytosine and high dose fluconazole is superior to fluconazole monotherapy for cryptococcal meningitis: a randomized trial in Malawi
BACKGROUND: Cryptococcal meningitis is a major cause of HIV-associated morbidity and mortality in Africa. Improved oral treatment regimens are needed, as amphotericin B is neither available nor feasible in many centers. Fluconazole 1200 mg/d is more fungicidal than 800 mg/d, but mortality remains un...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805957/ https://ncbi.nlm.nih.gov/pubmed/20038244 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/649861 |
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