Addition of Flucytosine to Fluconazole for the Treatment of Cryptococcal Meningitis in Africa: A Multicountry Cost-effectiveness Analysis

BACKGROUND: Mortality from cryptococcal meningitis remains very high in Africa. In the Advancing Cryptococcal Meningitis Treatment for Africa (ACTA) trial, 2 weeks of fluconazole (FLU) plus flucytosine (5FC) was as effective and less costly than 2 weeks of amphotericin-based regimens. However, many...

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Detalhes bibliográficos
Publicado no:Clin Infect Dis
Main Authors: Shiri, Tinevimbo, Loyse, Angela, Mwenge, Lawrence, Chen, Tao, Lakhi, Shabir, Chanda, Duncan, Mwaba, Peter, Molloy, Síle F, Heyderman, Robert S, Kanyama, Cecilia, Hosseinipour, Mina C, Kouanfack, Charles, Temfack, Elvis, Mfinanga, Sayoki, Kivuyo, Sokoine, Chan, Adrienne K, Jarvis, Joseph N, Lortholary, Olivier, Jaffar, Shabbar, Niessen, Louis W, Harrison, Thomas S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Articles and Commentaries
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912152/
https://ncbi.nlm.nih.gov/pubmed/30816418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciz163
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