Addition of Flucytosine to Fluconazole for the Treatment of Cryptococcal Meningitis in Africa: A Multicountry Cost-effectiveness Analysis

BACKGROUND: Mortality from cryptococcal meningitis remains very high in Africa. In the Advancing Cryptococcal Meningitis Treatment for Africa (ACTA) trial, 2 weeks of fluconazole (FLU) plus flucytosine (5FC) was as effective and less costly than 2 weeks of amphotericin-based regimens. However, many...

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Vydáno v:Clin Infect Dis
Hlavní autoři: Shiri, Tinevimbo, Loyse, Angela, Mwenge, Lawrence, Chen, Tao, Lakhi, Shabir, Chanda, Duncan, Mwaba, Peter, Molloy, Síle F, Heyderman, Robert S, Kanyama, Cecilia, Hosseinipour, Mina C, Kouanfack, Charles, Temfack, Elvis, Mfinanga, Sayoki, Kivuyo, Sokoine, Chan, Adrienne K, Jarvis, Joseph N, Lortholary, Olivier, Jaffar, Shabbar, Niessen, Louis W, Harrison, Thomas S
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912152/
https://ncbi.nlm.nih.gov/pubmed/30816418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciz163
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