Addition of Flucytosine to Fluconazole for the Treatment of Cryptococcal Meningitis in Africa: A Multicountry Cost-effectiveness Analysis

BACKGROUND: Mortality from cryptococcal meningitis remains very high in Africa. In the Advancing Cryptococcal Meningitis Treatment for Africa (ACTA) trial, 2 weeks of fluconazole (FLU) plus flucytosine (5FC) was as effective and less costly than 2 weeks of amphotericin-based regimens. However, many...

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Publicado en:Clin Infect Dis
Autores principales: Shiri, Tinevimbo, Loyse, Angela, Mwenge, Lawrence, Chen, Tao, Lakhi, Shabir, Chanda, Duncan, Mwaba, Peter, Molloy, Síle F, Heyderman, Robert S, Kanyama, Cecilia, Hosseinipour, Mina C, Kouanfack, Charles, Temfack, Elvis, Mfinanga, Sayoki, Kivuyo, Sokoine, Chan, Adrienne K, Jarvis, Joseph N, Lortholary, Olivier, Jaffar, Shabbar, Niessen, Louis W, Harrison, Thomas S
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2020
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Articles and Commentaries
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6912152/
https://ncbi.nlm.nih.gov/pubmed/30816418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciz163
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