Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak

Garlic constituent diallyl trisulfide (DATS) inhibits growth of cancer cells in vitro and in vivo by causing apoptosis, but the sequence of events leading to cell death is not fully understood. We now show that DATS treatment triggers mitochondria-mediated apoptosis program in human prostate cancer...

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Hlavní autoři: Kim, Young-Ae, Xiao, Dong, Xiao, Hui, Powolny, Anna A., Lew, Karen L., Reilly, Megan L., Zeng, Yan, Wang, Zhou, Singh, Shivendra V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805823/
https://ncbi.nlm.nih.gov/pubmed/17513609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-06-0754
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