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Diallyl Trisulfide-induced Apoptosis in Human Cancer Cells is Linked to Checkpoint Kinase 1-mediated Mitotic Arrest

Growth suppressive effect of diallyl trisulfide (DATS), a promising cancer chemopreventive constituent of garlic, against cultured human cancer cells correlates with checkpoint kinase 1 (Chk1)-mediated mitotic arrest, but the fate of the cells arrested in mitosis remains elusive. Using LNCaP and HCT...

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Bibliografiske detaljer
Main Authors: Xiao, Dong, Zeng, Yan, Singh, Shivendra V.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783910/
https://ncbi.nlm.nih.gov/pubmed/19459175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mc.20553
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