Prolonged ex vivo culture of human bone marrow mesenchymal stem cells influences their supportive activity toward NOD/SCID-repopulating cells and committed progenitor cells of B lymphoid and myeloid lineages

BACKGROUND: Bone marrow mesenchymal stem cells support proliferation and differentiation of hematopoietic progenitor cells in vitro. Since these cells constitute a rare subset of bone marrow cells, mesenchymal stem cell preparations for clinical purposes require a preparative step of ex vivo multipl...

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Main Authors: Briquet, Alexandra, Dubois, Sophie, Bekaert, Sandrine, Dolhet, Marie, Beguin, Yves, Gothot, André
Formato: Artigo
Idioma:Inglês
Publicado: Ferrata Storti Foundation 2010
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805732/
https://ncbi.nlm.nih.gov/pubmed/19713224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2009.008524
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