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RNA degradation compromises the reliability of microRNA expression profiling

BACKGROUND: MicroRNAs are small non-coding RNAs that post-transcriptionally regulate gene expression and their expression is frequently altered in human diseases, including cancer. To correlate clinically relevant parameters with microRNA expression, total RNA is frequently prepared from samples tha...

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Bibliografiske detaljer
Main Authors: Ibberson, David, Benes, Vladimir, Muckenthaler, Martina U, Castoldi, Mirco
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805631/
https://ncbi.nlm.nih.gov/pubmed/20025722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-9-102
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