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RNA degradation compromises the reliability of microRNA expression profiling

BACKGROUND: MicroRNAs are small non-coding RNAs that post-transcriptionally regulate gene expression and their expression is frequently altered in human diseases, including cancer. To correlate clinically relevant parameters with microRNA expression, total RNA is frequently prepared from samples tha...

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Bibliografiska uppgifter
Huvudupphovsmän: Ibberson, David, Benes, Vladimir, Muckenthaler, Martina U, Castoldi, Mirco
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805631/
https://ncbi.nlm.nih.gov/pubmed/20025722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-9-102
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