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RNA degradation compromises the reliability of microRNA expression profiling

BACKGROUND: MicroRNAs are small non-coding RNAs that post-transcriptionally regulate gene expression and their expression is frequently altered in human diseases, including cancer. To correlate clinically relevant parameters with microRNA expression, total RNA is frequently prepared from samples tha...

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Detalhes bibliográficos
Main Authors: Ibberson, David, Benes, Vladimir, Muckenthaler, Martina U, Castoldi, Mirco
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805631/
https://ncbi.nlm.nih.gov/pubmed/20025722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-9-102
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