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RNA degradation compromises the reliability of microRNA expression profiling

BACKGROUND: MicroRNAs are small non-coding RNAs that post-transcriptionally regulate gene expression and their expression is frequently altered in human diseases, including cancer. To correlate clinically relevant parameters with microRNA expression, total RNA is frequently prepared from samples tha...

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Bibliografische gegevens
Hoofdauteurs: Ibberson, David, Benes, Vladimir, Muckenthaler, Martina U, Castoldi, Mirco
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BioMed Central 2009
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805631/
https://ncbi.nlm.nih.gov/pubmed/20025722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-9-102
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