RNA degradation compromises the reliability of microRNA expression profiling

BACKGROUND: MicroRNAs are small non-coding RNAs that post-transcriptionally regulate gene expression and their expression is frequently altered in human diseases, including cancer. To correlate clinically relevant parameters with microRNA expression, total RNA is frequently prepared from samples tha...

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Detaylı Bibliyografya
Asıl Yazarlar: Ibberson, David, Benes, Vladimir, Muckenthaler, Martina U, Castoldi, Mirco
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2009
Konular:
Methodology article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805631/
https://ncbi.nlm.nih.gov/pubmed/20025722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-9-102
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