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PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G(1) cell cycle arrest in human glioblastoma cells

PTEN/MMAC1/TEP1 is a tumor suppressor that possesses intrinsic phosphatase activity. Deletions or mutations of its encoding gene are associated with a variety of human cancers. However, very little is known about the molecular mechanisms by which this important tumor suppressor regulates cell growth...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Li, Da-Ming, Sun, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC28055/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9860981/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.26.15406
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