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BRCA1-associated growth arrest is RB-dependent

BRCA1 is a susceptibility gene for breast and ovarian cancer with growth-inhibitory activity for which the mechanism of action remains unclear. When introduced into cells, BRCA1 inhibits growth of some but not all cell lines. In an attempt to uncover the mechanism of growth suppression by BRCA1, we...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Aprelikova, Olga N., Fang, Bruno S., Meissner, Eric G., Cotter, Shane, Campbell, Mel, Kuthiala, Aalok, Bessho, Mika, Jensen, Roy A., Liu, Edison T.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1999
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18378/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518542/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.11866
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