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BRCA1-associated growth arrest is RB-dependent

BRCA1 is a susceptibility gene for breast and ovarian cancer with growth-inhibitory activity for which the mechanism of action remains unclear. When introduced into cells, BRCA1 inhibits growth of some but not all cell lines. In an attempt to uncover the mechanism of growth suppression by BRCA1, we...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Aprelikova, Olga N., Fang, Bruno S., Meissner, Eric G., Cotter, Shane, Campbell, Mel, Kuthiala, Aalok, Bessho, Mika, Jensen, Roy A., Liu, Edison T.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1999
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18378/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10518542/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.21.11866
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