Identification and Characterization of a Novel Member of the Radical AdoMet Enzyme Superfamily and Implications for the Biosynthesis of the Hmd Hydrogenase Active Site Cofactor

The genetic context, phylogeny, and biochemistry of a gene flanking the H(2)-forming methylene-H(4)-methanopterin dehydrogenase gene (hmdA), here designated hmdB, indicate that it is a new member of the radical S-adenosylmethionine enzyme superfamily. In contrast to the characteristic CX(3)CX(2)C or...

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Detalhes bibliográficos
Main Authors: McGlynn, Shawn E., Boyd, Eric S., Shepard, Eric M., Lange, Rachel K., Gerlach, Robin, Broderick, Joan B., Peters, John W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Enzymes and Proteins
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805320/
https://ncbi.nlm.nih.gov/pubmed/19897660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.01125-09
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