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A Chemical Genetic Screen for Modulators of Exocytic Transport Identifies Inhibitors of a Transport Mechanism Linked to GTR2 Function

Membrane and protein traffic to the cell surface is mediated by partially redundant pathways that are difficult to perturb in ways that yield a strong phenotype. Such robustness is expected in a fine-tuned process, regulated by environmental cues, that is required for controlled cell surface growth...

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Bibliographic Details
Main Authors: Zhang, Lisha, Huang, Min, Harsay, Edina
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805290/
https://ncbi.nlm.nih.gov/pubmed/19897736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00184-09
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