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A high-throughput screen for chemical inhibitors of exocytic transport in yeast

Most of the components of the membrane and protein traffic machinery were discovered by perturbing their functions, either with bioactive compounds or by mutations. However, the mechanisms responsible for exocytic transport vesicle formation at the Golgi and endosomes are still largely unknown. Both...

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Main Authors: Zhang, Lisha, Nebane, N. Miranda, Wennerberg, Krister, Li, Yujie, Neubauer, Valerie, Hobrath, Judith V., McKellip, Sara, Rasmussen, Lynn, Shindo, Nice, Sosa, Melinda, Maddry, Joseph A., Ananthan, Subramaniam, Piazza, Gary A., White, E. Lucile, Harsay, Edina
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3090732/
https://ncbi.nlm.nih.gov/pubmed/20461743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200900681
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