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Influence of the MTHFR C677T polymorphism on MRI hyperintensity volume and cognition in geriatric depression

OBJECTIVE: The 5,10-methylenetetrahydrofolate reductase gene (MTHFR) has been linked to unipolar major depressive disorder (MDD) and MRI hyperintensities. We examined the relationship between the MTHFR C677T polymorphism (C677T) and a) geriatric depression, b) MRI hyperintense lesion volume, and c)...

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Auteurs principaux: Hong, Edmund D., Taylor, Warren D., McQuoid, Douglas R., Potter, Guy G., Payne, Martha E., Ashley-Koch, Allison, Steffens, David C.
Format: Artigo
Langue:Inglês
Publié: 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805265/
https://ncbi.nlm.nih.gov/pubmed/19910873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JGP.0b013e3181aad5b2
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