Gene variants of the renin-angiotensin system are associated with accelerated hippocampal volume loss and cognitive decline in old age

OBJECTIVE: Genetic factors confer risk for neuropsychiatric phenotypes, but the polygenic etiology of these phenotypes makes identification of genetic culprits challenging. An approach to this challenge is to examine the effects of genetic variation on relevant endophenotypes, such as hippocampal vo...

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Detalhes bibliográficos
Publicado no:Am J Psychiatry
Main Authors: Zannas, Anthony S., McQuoid, Douglas R., Payne, Martha E, MacFall, James R., Ashley-Koch, Allison, Steffens, David C., Potter, Guy G., Taylor, Warren D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329281/
https://ncbi.nlm.nih.gov/pubmed/25124854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2014.13111543
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