Učitavanje...

Age-dependent deterioration of nuclear pore complexes causes a loss of nuclear integrity in post-mitotic cells

In dividing cells, nuclear pore complexes (NPCs) disassemble during mitosis and reassemble into the newly forming nuclei. However, the fate of these multi-protein transport channels in post-mitotic cells, where the mitotic renewal of pores is absent, is unknown. Here we show that NPCs, unlike other...

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Bibliografski detalji
Glavni autori: D’Angelo, Maximiliano A., Raices, Marcela, Panowski, Siler H., Hetzer, Martin W.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805151/
https://ncbi.nlm.nih.gov/pubmed/19167330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.11.037
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