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Nkx2.2 Regulates β-Cell Function in the Mature Islet

Nkx2.2 is a homeodomain transcription factor that is critical for pancreatic endocrine cell specification and differentiation in the developing mouse embryo. The purpose of this study was to determine whether Nkx2.2 is also required for the maintenance and function of the mature β-cell in the postna...

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Detalles Bibliográficos
Autores principales: Doyle, Michelle J., Sussel, Lori
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805073/
https://ncbi.nlm.nih.gov/pubmed/17456846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db06-1766
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