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The role of HMGCR alternative splicing in statin efficacy
Statins, or 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) inhibitors, are widely prescribed to lower plasma cholesterol levels and reduce cardiovascular disease (CVD) risk. Despite the well documented efficacy of statins, there is large inter-individual variation in response. Using a panel...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805071/ https://ncbi.nlm.nih.gov/pubmed/20005478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tcm.2009.10.003 |
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