Coordinately Regulated Alternative Splicing of Genes Involved in Cholesterol Biosynthesis and Uptake

Genes involved in cholesterol biosynthesis and uptake are transcriptionally regulated in response to cellular sterol content in a coordinated manner. A number of these genes, including 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMGCR) and LDL receptor (LDLR), undergo alternative splicing, resu...

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Detalhes bibliográficos
Main Authors: Medina, Marisa Wong, Gao, Feng, Naidoo, Devesh, Rudel, Lawrence L., Temel, Ryan E., McDaniel, Allison L., Marshall, Stephanie M., Krauss, Ronald M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3084847/
https://ncbi.nlm.nih.gov/pubmed/21559365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019420
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