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CHANGES IN THE MOUSE ESTRUS CYCLE IN RESPONSE TO Brca1 INACTIVATION SUGGEST A POTENTIAL LINK BETWEEN RISK FACTORS FOR FAMILIAL AND SPORADIC OVARIAN CANCER
Menstrual cycle activity is the most important risk factor for sporadic serous ovarian carcinoma while a germline mutation in BRCA1 is the most important risk factor for the familial form. Given the rarity of BRCA1 mutations in sporadic ovarian cancers, we hypothesized that BRCA1 influences the mens...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2805040/ https://ncbi.nlm.nih.gov/pubmed/20028858 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3232 |
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