CHANGES IN THE MOUSE ESTRUS CYCLE IN RESPONSE TO Brca1 INACTIVATION SUGGEST A POTENTIAL LINK BETWEEN RISK FACTORS FOR FAMILIAL AND SPORADIC OVARIAN CANCER

Menstrual cycle activity is the most important risk factor for sporadic serous ovarian carcinoma while a germline mutation in BRCA1 is the most important risk factor for the familial form. Given the rarity of BRCA1 mutations in sporadic ovarian cancers, we hypothesized that BRCA1 influences the mens...

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Bibliografische gegevens
Hoofdauteurs: Hong, Hao, Yen, Hai-Yun, Brockmeyer, Amy, Liu, Ying, Chodankar, Rajas, Pike, Malcolm C, Stanczyk, Frank Z, Maxson, Robert, Dubeau, Louis
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2009
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2805040/
https://ncbi.nlm.nih.gov/pubmed/20028858
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-3232
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