Recombinant Proapoptotic M. tuberculosis Generates CD8(+) T-cell Responses Against Human Immunodeficiency Virus Type 1 Env and M. tuberculosis in Neonatal Mice

M. bovis BCG is an attractive vaccine vector against breast milk HIV transmission because it elicits Th1-type responses in newborns. However, BCG causes disease in HIV-infected infants. Genetically attenuated M. tuberculosis (Mtb) mutants represent a safer alternative for immunocompromised populatio...

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Hlavní autoři: Ranganathan, Uma Devi K, Larsen, Michelle H., Kim, John, Porcelli, Steven A., Jacobs, William R., Fennelly, Glenn J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2804991/
https://ncbi.nlm.nih.gov/pubmed/19808028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.09.087
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