Generation of CD8(+) T-Cell Responses by a Recombinant Nonpathogenic Mycobacterium smegmatis Vaccine Vector Expressing Human Immunodeficiency Virus Type 1 Env

Because the vaccine vectors currently being evaluated in human populations all have significant limitations in their immunogenicity, novel vaccine strategies are needed for the elicitation of cell-mediated immunity. The nonpathogenic, rapidly growing mycobacterium Mycobacterium smegmatis was enginee...

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Detalhes bibliográficos
Main Authors: Cayabyab, Mark J., Hovav, Avi-Hai, Hsu, Tsungda, Krivulka, Georgia R., Lifton, Michelle A., Gorgone, Darci A., Fennelly, Glenn J., Haynes, Barton F., Jacobs, William R., Letvin, Norman L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367151/
https://ncbi.nlm.nih.gov/pubmed/16439521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.80.4.1645-1652.2006
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