Transcriptional activation of HLA-DR alpha by interferon gamma requires a trans-acting protein.

Stimulation of the human epithelial-like cell line, HeLa, with interferon gamma (IFN-gamma) induces steady-state levels of HLA-DR alpha mRNA. Using a sensitive RNase-mapping procedure, we detect induced HLA-DR alpha mRNA as early as 8 hr after IFN-gamma treatment; maximal accumulation occurs by 48 h...

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Hlavní autoři: Blanar, M A, Boettger, E C, Flavell, R A
Médium: Artigo
Jazyk:Inglês
Vydáno: 1988
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC280497/
https://ncbi.nlm.nih.gov/pubmed/3133656
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