Transcriptional activation of HLA-DR alpha by interferon gamma requires a trans-acting protein.
Stimulation of the human epithelial-like cell line, HeLa, with interferon gamma (IFN-gamma) induces steady-state levels of HLA-DR alpha mRNA. Using a sensitive RNase-mapping procedure, we detect induced HLA-DR alpha mRNA as early as 8 hr after IFN-gamma treatment; maximal accumulation occurs by 48 h...
Shranjeno v:
| izdano v: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
1988
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280497/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3133656/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4672 |
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