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Transcriptional activation of HLA-DR alpha by interferon gamma requires a trans-acting protein.

Stimulation of the human epithelial-like cell line, HeLa, with interferon gamma (IFN-gamma) induces steady-state levels of HLA-DR alpha mRNA. Using a sensitive RNase-mapping procedure, we detect induced HLA-DR alpha mRNA as early as 8 hr after IFN-gamma treatment; maximal accumulation occurs by 48 h...

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Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Blanar, M A, Boettger, E C, Flavell, R A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 1988
Aiheet:
Linkit:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280497/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3133656/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4672
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