In vitro expression in eukaryotic cells of a prion protein gene cloned from scrapie-infected mouse brain.
It has been proposed that the causative agent of scrapie represents a class of infectious particle that is devoid of nucleic acid and that an altered form of the endogenous prion protein (PrP) is the agent. However, it has been difficult to exclude the possibility that PrP purified from scrapie tiss...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1988
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280494/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2898780/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.13.4657 |
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