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In vitro expression in eukaryotic cells of a prion protein gene cloned from scrapie-infected mouse brain.

It has been proposed that the causative agent of scrapie represents a class of infectious particle that is devoid of nucleic acid and that an altered form of the endogenous prion protein (PrP) is the agent. However, it has been difficult to exclude the possibility that PrP purified from scrapie tiss...

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Main Authors: Caughey, B, Race, R E, Vogel, M, Buchmeier, M J, Chesebro, B
格式: Artigo
語言:Inglês
出版: 1988
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC280494/
https://ncbi.nlm.nih.gov/pubmed/2898780
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